Research groups

Our lab has a broad interest in the interplay between skin stroma, immune cells, and pathogens in health and disease, ranging from clinical studies, translational research all the way to fundamental research.

The DMOT research group focuses on the development of in vitro and in vivo models of human diseases with a particular focus on vascular diseases affecting the skin, also including the development of novel pharmaceutical approaches.

Therapy resistance and metastatic propensity are hallmarks of melanoma, the most aggressive form of skin cancer. Our scientific focus is to characterise the pathomechanisms of resistance to immune or targeted therapy in melanoma.

Our studies aim to analyse gene function in healthy and pathological conditions, e.g. in tumour development, using the mouse as a model organism, but also employing patient-derived samples.

We focus on diagnostic skin imaging, artificial intelligence, machine learning, simulation, computational biology, and morphometry and morphogenesis.

The Georg Stary Lab at the Department of Dermatology, Medical University of Vienna focuses on “Translational Immunology in Mucosa and Skin (TIMS)”.

We investigate basic mechanisms how vessels in the skin facilitate barrier function and regulate exchange and we search for ways to support vascular function in disease.

Our scientific focus is to characterise the pathomechanisms of resistance to immune or targeted therapy in melanoma and the influence of the tumour microenvironment using various proteomic technologies. 

The primary objective of my research group is to elucidate the specific cell types and underlying mechanisms responsible for the development of keloids and hypertrophic scars.

We aim at dissecting how targeting fibroblasts can be used to redirect wound repair into scarless healing, and to develop therapies for fibrotic skin diseases like scleroderma or keloids, and skin cancer.

Human Papillomavirus-like particles (VLP) are highly immunogenic nanoparticles that prevent HPV infection and disease, in particular cervical and other anogenital and oropharyngeal cancers and warts.

Our team engages in basic research and clinical studies investigating infectious diseases caused by parasites (scabies mites) or certain viruses (human and mouse papillomavirus, Mpox virus, SARS-CoV-2).  

Our lab takes a translational, bioinformatics-based approach to investigate key immunodermatological diseases as well as primary cutaneous lymphomas.

We investigate stress and aging of the skin, and what role bioactive lipids have in these processes. With analytical multimodal imaging of skin we localize novel parameters of aging and senescence.

We focus on the processes leading to innate immune cell activation on a functional systems biology and functional cellular level, and reprogram their epigenomic potential to elicit improved responses.

The experimental allergy laboratory focuses on unraveling the mechanisms underlying the initiation and perpetuation of allergic asthma and food allergy using in vivo disease models.

Investigations about the physiology of the skin immune system and the origin, relationship and function of skin leukocytes [e.g. Langerhans cells (image)] applying cutting edge technology.

Our aim is to determine the molecular control of the skin barrier and skin appendages. We study the biochemistry and evolutionary genetics of the skin with a focus on functions of epithelial cells.

Our research focuses on chronic inflammatory skin diseases such as atopic dermatitis and skin hypersensitivity reactions, but also malignancies derived from immune cells such as primary cutaneous T- and B-cell lymphomas.

Erwin Tschachler  was elected Editor in Chief of the Journal of Investigative Dermatology (JID) in May 2021 by the Board of the Society of Investigative Dermatology (SID). His term as Editor in Chief of the Journal started in June 2022.