Selected Publications

A full list of publications can be found on pubmed

Selected publications:

• CAF variants control the tumor-immune microenvironment and predict skin cancer malignancyAgnes Forsthuber, Ana Korosec, Tina Jacob, Bertram Aschenbrenner, Karl Annusver, Sophie Frech, Kim Purkhauser, Natalia Krajic, Katharina Lipp, Franziska Werner, Vy Nguyen, Johannes Griss, Wolfgang Bauer, Ana Soler Cardona, Benedikt Weber, Wolfgang Weninger, Bernhard Gesslbauer, Clement Staud, Jakob Nedomansky, Christine Radtke, Stephan N. Wagner, Peter Petzelbauer, Maria Kasper*, Beate M. Lichtenberger*.https://doi.org/10.1101/2023.05.03.539213

• A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. Almet AA, Yuan H, Annusver K, Ramos R, Liu Y, Wiedemann J, Sorkin DH, Landén NX, Sonkoly E, Haniffa M, Nie Q, Lichtenberger BM, Luecken MD, Andersen B, Tsoi LC, Watt FM, Gudjonsson JE, Plikus MV, Kasper M. J Invest Dermatol. 2023 Sep;143(9):1667-1677. doi: 10.1016/j.jid.2023.03.1679.

• Molecular and spatial design of early skin developmentTina Jacob, Karl Annusver, Paulo Czarnewski, Tim Dalessandri, Maria Eleni Kastriti, Chiara Levra Levron, Marja L Mikkola, Michael Rendl, Beate M Lichtenberger, Giacomo Donati, Åsa Björklund, Maria Kasper.bioRxiv 2022.12.28.522081; doi: https://doi.org/10.1101/2022.12.28.522081. (Accepted at Dev. Cell)
• Myofibroblast stroma differentiation in infiltrative basal cell carcinoma is accompanied by regulatory T-cells. Ressler JM, Zila N, Korosec A, Yu J, Silmbrod R, Bachmayr V, Tittes J, Strobl J, Lichtenberger BM, Hoeller C, Petzelbauer P. J Cutan Pathol. 2023 Jun;50(6):544-551. doi: 10.1111/cup.14381.
• Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration during Wound Healing. Frech S, Forsthuber A, Korosec A, Lipp K, Kozumov V, Lichtenberger BM. J Invest Dermatol. 2022 Jun;142(6):1737-1748.e5. doi: 10.1016/j.jid.2021.11.026.
• Mus musculus papillomavirus 1 is a key driver of skin cancer development upon immunosuppression. Dorfer S, Strasser K, Schröckenfuchs G, Bonelli M, Bauer W, Kittler H, Cataisson C, Fischer MB, Lichtenberger BM and Handisurya A. Am J Transplant 2020 Oct, doi: 10.1111/ajt.16358.     
• Cellular heterogeneity and microenvironmental control of skin cancer.  Lichtenberger BM*, Kasper M*. J Intern Med. 2020 Sep 25. doi: 10.1111/joim.13177.
• Deciphering the functional heterogeneity of skin fibroblasts using single-cell RNA sequencing. Vorstandlechner V, Laggner M, Kalinina P, Haslik W, Radtke C, Shaw L, Lichtenberger BM, Tschachler E, Ankersmit HJ, Mildner M. FASEB J 2020 Mar, PMID: 31930613
• Inhibition of p38/MK2 Signaling Prevents Vascular Invasion of Melanoma. Wenzina J, Holzner S, Puujalka E, Cheng PF, Forsthuber A, Neumüller K, Schossleitner K, Lichtenberger BM, Levesque MP, Petzelbauer P. JID 2020 Apr. PMID:  31622599
• Isolation of Papillary and Reticular Fibroblasts from Human Skin by Fluorescence-activated Cell Sorting Korosec A, Frech S, Lichtenberger BM. JoVE 2019 May, PMID: 31132050
• Lineage identity and location within the dermis determine the function of papillary and reticular fibroblasts in human skin. Korosec A, Frech S, Gesslbauer B, Vierhapper M, Radtke C, Petzelbauer P, Lichtenberger BM. J Invest Dermatol. 2018 Sep, PMID: 30179601
• An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.
  Liakath-Ali K, Mills EW, Sequeira I, Lichtenberger BM, Pisco AO, Sipilä KH, Mishra A, Yoshikawa H, Wu CC, Ly T, Lamond AI, Adham IM, Green R, Watt FM. Nature. 2018 Apr;556(7701):376-380. doi: 10.1038/s41586-018-0032-3.
• β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis. Mastrogiannaki M, Lichtenberger BM, Reimer A, Collins CA, Driskell RR, Watt FM. J Invest Dermatol. 2016 Jun, PMID: 26902921
• Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages. Lichtenberger BM, Mastrogiannaki M, Watt FM. Nat Commun. 2016 Feb 3, PMID: 26837596
• Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation. Kaushal GS, Rognoni E, Lichtenberger BM, Driskell RR, Kretzschmar K, Hoste E, Watt FM. J Invest Dermatol. 2015 Dec, PMID: 26288357
• Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors. Donati G, Proserpio V, Lichtenberger BM, Natsuga K, Sinclair R, Fujiwara H, Watt FM. Proc Natl Acad Sci U S A. 2014 Apr 15, PMID: 24706781
• Distinct fibroblast lineages determine dermal architecture in skin development and repair. Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM. Nature. 2013 Dec 12, doi: 10.1038/nature12783.
• Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis. Winter M, Moser MA, Meunier D, Fischer C, Machat G, Mattes K, Lichtenberger BM, Brunmeir R, Weissmann S, Murko C, Humer C, Meischel T, Brosch G, Matthias P, Sibilia M, Seiser C. EMBO J. 2013 Dec 11, PMID: 24240174
• Epidermal EGFR controls cutaneous host defense and prevents inflammation. Lichtenberger BM, Gerber PA, Holcmann M, Buhren BA, Amberg N, Smolle V, Schrumpf H, Boelke E, Ansari P, Mackenzie C, Wollenberg A, Kislat A, Fischer JW, Röck K, Harder J, Schröder JM, Homey B, Sibilia M. Sci Transl Med. 2013 Aug 21, PMID: 23966300
• Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development.  Lichtenberger BM, Tan PK, Niederleithner H, Ferrara N, Petzelbauer P, Sibilia M. Cell. 2010 Jan 22, PMID: 20141840