Delineating the role of innate immune cells in leukocyte trafficking during sterile inflammation.
A plethora of human disorders are initiated by overt inflammation within tissues. Utilizing complex immunological models, transgenic reporter mice along with intravital multiphoton imaging, we aim to decipher the complex relationship between tissue-resident and infiltrating immune cells. The use of these model systems helps to develop cellular interactome and delineates the orchestration of pathological inflammation.
People involved in the project: Shweta Tikoo, Rohit Jain